Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27943670 | 0.87 | MEN1 (0.64) | KDM4EALDH1A1LMNASMN1; SMN2KCNA5 | |
| SCHEMBL30600005 | 0.81 | MAPT (0.64) | HTTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL5315377 | 0.79 | LTA4H (0.76) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL10680888 | 0.79 | MEN1 (0.47) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8738577 | 0.77 | PARP14 (0.73) | HTTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL21240918 | 0.77 | SLC6A7 (0.63) | HTTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL5312292 | 0.77 | LMNA (0.67) | HTTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL5312685 | 0.76 | LTA4H (0.76) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL3074396 | 0.75 | MEN1 (0.68) | KDM4EALDH1A1LMNASMN1; SMN2KCNA5 | |
| SCHEMBL16151037 | 0.74 | MAPT (0.70) | HTTALDH1A1LMNASLC6A7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751169-A | N- (2-oxo propyl) acetamide derivative and preparation method and application thereof | 重庆市畜牧科学院 | 2023-09-15 | — | — | CN | disclosed |