Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110273 | 1.00 | PTGS2 (0.43) | PTGS2SCN9ACYP2C9PDPK1CNR1 | |
| SCHEMBL30602812 | 0.85 | PTGS2 (0.43) | PTGS2SCN9ACYP2C9PDPK1CHRNA7 | |
| SCHEMBL30602805 | 0.82 | PTGS2 (0.41) | PTGS2SCN9ACYP2C9PDPK1CNR1 | |
| SCHEMBL30602796 | 0.80 | RARG (0.40) | PTGS2SCN9ACYP2C9PDPK1CNR1 | |
| SCHEMBL26106990 | 0.80 | RARG (0.40) | PTGS2SCN9ACYP2C9PDPK1CNR1 | |
| SCHEMBL30602799 | 0.76 | BMP1 (0.46) | PTGS2SCN9APTGS1 | |
| SCHEMBL26109702 | 0.76 | BMP1 (0.46) | PTGS2SCN9APTGS1 | |
| SCHEMBL30602801 | 0.75 | NR3C1 (0.49) | — | |
| SCHEMBL61336 | 0.72 | KIF11 (0.55) | PTGS2PTGS1 | |
| SCHEMBL30056430 | 0.71 | TEAD1 (0.47) | PTGS2CYP2C9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |