Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 8/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26276088 | 0.83 | ACLY (0.50) | ACLYTAS2R14MAOAMAOBCASP3 | |
| SCHEMBL22718046 | 0.81 | ACLY (0.49) | ACLYTAS2R14MAOAMAOBCASP3 | |
| SCHEMBL7540063 | 0.81 | SIRT2 (0.48) | TAS2R14MAOBALDH1A1TUBB4ATUBB | |
| SCHEMBL7535538 | 0.79 | PKM (0.56) | HSD11B1TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL22718182 | 0.79 | TAS2R14 (0.56) | ACLYTAS2R14STAT3MAPTTP53 | |
| SCHEMBL6958238 | 0.78 | TAS2R14 (0.64) | ACLYTAS2R14MAOAMAOBCASP3 | |
| SCHEMBL29074172 | 0.78 | TAS2R14 (0.39) | ACLYTAS2R14HSD11B1ALDH1A1APLNR | |
| SCHEMBL30129698 | 0.78 | TAS2R14 (0.39) | ACLYTAS2R14HSD11B1ALDH1A1APLNR | |
| SCHEMBL12855750 | 0.77 | ALDH1A1 (0.43) | ACLYALDH1A1MAPT | |
| SCHEMBL29648376 | 0.76 | MEN1 (0.49) | ACLYTAS2R14MAOAMAOBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095828-A | Indazole compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |