Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17543991 | 0.79 | CHRNA7 (0.47) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL28874935 | 0.77 | TERT (0.56) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL4212685 | 0.76 | GAA (0.67) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL28306659 | 0.76 | TERT (0.57) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL4210647 | 0.76 | HTR1A (0.51) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL24532569 | 0.74 | LMNA (0.45) | ALDH1A1GAAKDM4EPOLBMEN1 | |
| SCHEMBL29681492 | 0.74 | LMNA (0.45) | ALDH1A1GAAKDM4EPOLBMEN1 | |
| SCHEMBL2418717 | 0.74 | HTR3E (0.61) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL27778735 | 0.74 | CBFB (0.55) | CHRNA7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL4221038 | 0.73 | IGF1R (0.50) | CHRNA7ALDH1A1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |