Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.47 |
| ▸ | TDO2 | P48775 | 4/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17738420 | 1.00 | IDO1 (0.47) | IDO1TDO2METAP2 | |
| SCHEMBL17738422 | 0.86 | IDO1 (0.41) | IDO1TDO2METAP2 | |
| SCHEMBL17738413 | 0.84 | IDO1 (0.46) | IDO1TDO2METAP2 | |
| SCHEMBL17739216 | 0.80 | CYP11B2 (0.43) | IDO1 | |
| SCHEMBL20001898 | 0.80 | TDO2 (0.46) | IDO1TDO2 | |
| SCHEMBL20002376 | 0.80 | TDO2 (0.46) | IDO1TDO2 | |
| SCHEMBL20001900 | 0.78 | TDO2 (0.47) | IDO1TDO2 | |
| SCHEMBL21894582 | 0.76 | IDO1 (0.44) | IDO1TDO2METAP2 | |
| SCHEMBL17739557 | 0.76 | METAP2 (0.46) | IDO1TDO2METAP2 | |
| SCHEMBL20042261 | 0.75 | TDO2 (0.44) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110392678-B | Compounds and methods for IDO and TDO modulation, and indications therefor | 普莱希科公司 | 2023-10-20 | — | — | CN | disclosed |