Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656930 | 1.00 | KMT2A (0.45) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL28633462 | 0.90 | KMT2A (0.53) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL28925117 | 0.90 | MEN1 (0.50) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL30604612 | 0.87 | KMT2A (0.47) | KMT2AMEN1TDP1TSHRALDH1A1 | |
| SCHEMBL28638917 | 0.87 | KMT2A (0.47) | KMT2AMEN1TDP1TSHRALDH1A1 | |
| SCHEMBL30604571 | 0.82 | KMT2A (0.53) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL28652153 | 0.82 | KMT2A (0.53) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL28639031 | 0.81 | KMT2A (0.57) | KMT2AHDAC4HDAC1HDAC6MEN1 | |
| SCHEMBL30604607 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPTDHPSALDH1A1 | |
| SCHEMBL28645344 | 0.79 | KMT2A (0.41) | KMT2ATP53TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493438-B | Tetrahydroisoquinoline compounds | 南京再明医药有限公司 | 2023-10-20 | — | — | CN | disclosed |