Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439409 | 0.84 | TSHR (0.46) | TSHRALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28061876 | 0.79 | ALDH1A1 (0.50) | TSHRGAACYP2C19ALDH1A1HPGD | |
| SCHEMBL9950596 | 0.73 | ALDH1A1 (0.62) | TSHRGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10780992 | 0.73 | HPGD (0.59) | TSHRGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL28360457 | 0.72 | PTPN2 (0.49) | TSHRALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28479127 | 0.72 | MAPT (0.52) | TSHRALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27402941 | 0.72 | NPC1 (0.56) | TSHRALDH1A1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2145842 | 0.70 | CES2 (0.52) | GAAALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL9548507 | 0.70 | ALDH1A1 (0.54) | TSHRGAACYP2C19ALDH1A1HPGD | |
| SCHEMBL10499420 | 0.69 | NR4A1 (0.55) | GAAALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221749-A1 | THREE-FUNCTIONAL PSEUDO-PEPTIDIC REAGENT, AND USES AND APPLICATIONS THEREOF | UNIVERSITE DE ROUEN | 2010-09-02 | — | — | US | claimed |
| US-20100221749-A1 | THREE-FUNCTIONAL PSEUDO-PEPTIDIC REAGENT, AND USES AND APPLICATIONS THEREOF | UNIVERSITE DE ROUEN | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221749-A1 | THREE-FUNCTIONAL PSEUDO-PEPTIDIC REAGENT, AND USES AND APPLICATIONS THEREOF | DNPEP, PEPD, LNPEP | TSHR 1704/4885GAA 392/4885CYP2C19 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.