Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.65 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609680 | 0.92 | MTNR1A (0.72) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL4720318 | 0.88 | MTNR1A (0.82) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL12302912 | 0.82 | MTNR1A (0.73) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL30605277 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL25938747 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL8642683 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL1724757 | 0.80 | MTNR1A (0.70) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL31184635 | 0.79 | POLB (0.53) | ALDH1A1POLB | |
| SCHEMBL31184396 | 0.79 | POLB (0.53) | ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL31185115 | 0.78 | POLB (0.52) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179031-A1 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2025-06-05 | — | — | US | disclosed |
| WO-2023147485-A2 | PROTEASOME ENHANCERS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179031-A1 | PROTEASOME ENHANCERS AND USES THEREOF | PSME3, PSMG3, PSME1 | MTNR1A 1726/4885MTNR1B 2338/4885TUBB4A 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.