Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488492 | 1.00 | IDO1 (0.39) | IDO1MAP4K4MAPK10ACE2DYRK1A | |
| SCHEMBL21463384 | 0.79 | TDO2 (0.46) | MAP4K4DYRK1ACD44GSK3B | |
| SCHEMBL21463603 | 0.75 | FEN1 (0.33) | IDO1MAP4K4ALOX5APALDH1A1CD44 | |
| SCHEMBL30615396 | 0.75 | FEN1 (0.33) | IDO1MAP4K4ALOX5APALDH1A1CD44 | |
| SCHEMBL15364728 | 0.74 | IMPDH2 (0.51) | ACE2ATAD2ALDH1A1CD44HSD17B10 | |
| SCHEMBL28823621 | 0.73 | MAP4K4 (0.36) | MAP4K4MAPK10ALOX5APFYNFEN1 | |
| SCHEMBL31504094 | 0.73 | IDO1 (0.42) | IDO1MAP4K4HKDC1KDM4EMEN1 | |
| SCHEMBL23090584 | 0.72 | TGFBR1 (0.47) | MAP4K4DYRK1AALOX5APFEN1DHFR | |
| SCHEMBL17427069 | 0.72 | NISCH (0.42) | IDO1ALDH1A1HSD17B10GSK3BKDM4E | |
| SCHEMBL22912663 | 0.72 | IDO1 (0.55) | IDO1MAPK10DYRK1AALOX5APALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |