Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177830 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL22010011 | 0.82 | HPGD (0.67) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL1610173 | 0.78 | POLB (0.76) | ALDH1A1LMNASMN1; SMN2TSHRALPL | |
| SCHEMBL14606081 | 0.78 | KMT2A (0.65) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL27895613 | 0.74 | SMN1; SMN2 (0.63) | ALDH1A1LMNASMN1; SMN2TSHRALPL | |
| SCHEMBL30620401 | 0.73 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL24209664 | 0.72 | ALPL (0.73) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL27303492 | 0.72 | MAPT (0.78) | ALDH1A1LMNASMN1; SMN2TSHRHPGD | |
| SCHEMBL10678975 | 0.71 | SMN1; SMN2 (0.57) | ALDH1A1LMNASMN1; SMN2TSHRALPL | |
| SCHEMBL4159127 | 0.71 | ALPL (0.78) | ALDH1A1LMNASMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4508038-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | The United States Government as represented by the Department of Veterans Affairs (US) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023201374-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2023-10-19 | — | — | WO | disclosed |