Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645130 | 1.00 | CSNK1D (0.37) | CSNK1DCSNK1EGRIA1MMP13TGFBR1 | |
| SCHEMBL30622921 | 0.90 | NR1H2 (0.40) | MMP13UGCGSETD7 | |
| SCHEMBL26645124 | 0.90 | NR1H2 (0.40) | MMP13UGCGSETD7 | |
| SCHEMBL29308625 | 0.88 | CSNK1D (0.39) | CSNK1DCSNK1EGRIA1MMP13TGFBR1 | |
| SCHEMBL26645086 | 0.86 | CSNK1E (0.39) | CSNK1DCSNK1EUGCGMEN1KMT2A | |
| SCHEMBL30622831 | 0.85 | MAPK14 (0.43) | CSNK1DCSNK1EGRIA1 | |
| SCHEMBL30622940 | 0.79 | CSNK1D (0.37) | CSNK1DCSNK1EGRIA1MMP13TGFBR1 | |
| SCHEMBL30622815 | 0.79 | CSNK1D (0.37) | CSNK1DCSNK1EGRIA1MMP13TGFBR1 | |
| SCHEMBL29308624 | 0.79 | GRM5 (0.38) | CSNK1DCSNK1EMMP13HDAC1HDAC2 | |
| SCHEMBL16711450 | 0.79 | CSNK1E (0.52) | CSNK1DCSNK1EGRIA1MMP13TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |