Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622921 | 1.00 | NR1H2 (0.40) | NR1H2NR1H3MAPTGPR119SMO | |
| SCHEMBL30622862 | 0.90 | CSNK1D (0.37) | UGCGMMP13SETD7 | |
| SCHEMBL26645130 | 0.90 | CSNK1D (0.37) | UGCGMMP13SETD7 | |
| SCHEMBL26645645 | 0.87 | SMO (0.41) | SMOHTR3AUGCGCHRNB2CHRNB4 | |
| SCHEMBL30623093 | 0.84 | TRPM2 (0.35) | SMOHTR3AUGCGCHRNB2CHRNB4 | |
| SCHEMBL30622801 | 0.80 | NR1H2 (0.39) | NR1H2NR1H3MAPTGPR119SMO | |
| SCHEMBL30622988 | 0.80 | NR1H2 (0.39) | NR1H2NR1H3MAPTGPR119SMO | |
| SCHEMBL26645635 | 0.80 | MAPT (0.46) | MAPTGPR119P2RY14MMP13HDAC4 | |
| SCHEMBL30623037 | 0.78 | NR1H2 (0.43) | NR1H2NR1H3MAPTGPR119EIF2AK4 | |
| SCHEMBL29308625 | 0.78 | CSNK1D (0.39) | UGCGMMP13SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |