Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645130 | 0.88 | CSNK1D (0.37) | CSNK1DCSNK1EHDAC2HDAC1TGFBR1 | |
| SCHEMBL30622862 | 0.88 | CSNK1D (0.37) | CSNK1DCSNK1EHDAC2HDAC1TGFBR1 | |
| SCHEMBL24276764 | 0.87 | MAP4K4 (0.33) | CSNK1EHDAC2HDAC1MAP4K4POLB | |
| SCHEMBL30622831 | 0.85 | MAPK14 (0.43) | CSNK1DCSNK1EGRIA1 | |
| SCHEMBL29308624 | 0.79 | GRM5 (0.38) | CSNK1DCSNK1EHDAC2HDAC1MMP13 | |
| SCHEMBL29308619 | 0.78 | MAP4K4 (0.36) | HDAC1MAP4K4SETD7 | |
| SCHEMBL30622921 | 0.78 | NR1H2 (0.40) | MMP13UGCGSETD7 | |
| SCHEMBL26645124 | 0.78 | NR1H2 (0.40) | MMP13UGCGSETD7 | |
| SCHEMBL30622756 | 0.77 | GRM5 (0.45) | HDAC2HDAC1MMP13MEN1KMT2A | |
| SCHEMBL30622975 | 0.76 | MAPK14 (0.44) | CSNK1DGRIA1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037339-B2 | Substituted imidazoles as GLP-1 receptor agonists | ECCOGENE INC. (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037339-B2 | Substituted imidazoles as GLP-1 receptor agonists | GLP1R, GIPR, SLC5A1 | CSNK1D 1243/4885CSNK1E 1569/4885HDAC2 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.