Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | PKLR | P30613 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790743 | 0.82 | CA1 (0.49) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL19280567 | 0.80 | KMT2A (0.67) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL30626035 | 0.80 | KMT2A (0.67) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL544826 | 0.75 | HTR6 (0.44) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL16467626 | 0.72 | PKM (0.45) | PKMPKLRHTR6LMNAKEAP1 | |
| SCHEMBL8202370 | 0.72 | PKM (0.45) | KMT2APKMPKLRHTR6SMN1; SMN2 | |
| SCHEMBL3792465 | 0.72 | TDP1 (0.56) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL15453544 | 0.72 | SLC22A12 (0.41) | KMT2AMEN1PKMPKLRHTR6 | |
| SCHEMBL30626033 | 0.72 | TDP1 (0.51) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL30626037 | 0.72 | PGR (0.54) | CA1CA2CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186028-A | Thiadiazole amide compound containing sulfonate structure, and preparation method and application thereof | 贵州大学 | 2023-12-08 | — | — | CN | disclosed |