Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153840 | 1.00 | IDO1 (0.50) | IDO1TDO2XDHMEN1KMT2A | |
| SCHEMBL5905968 | 0.80 | IDO1 (0.49) | IDO1TDO2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22206486 | 0.73 | CYP11B1 (0.47) | IDO1TDO2XDHMEN1KMT2A | |
| SCHEMBL5906231 | 0.72 | LMNA (0.44) | TDO2MEN1KMT2ATDP1POLB | |
| SCHEMBL20599778 | 0.71 | DAO (0.36) | IDO1TDO2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5906391 | 0.71 | PKM (0.46) | IDO1TDO2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22564074 | 0.70 | MGLL (0.46) | MEN1KMT2A | |
| SCHEMBL11518915 | 0.68 | MAPT (0.46) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7660286 | 0.68 | MAPT (0.46) | IDO1TDO2MEN1KMT2AGPR55 | |
| SCHEMBL29922845 | 0.68 | CMA1 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203205-A | Triazolone, tetrazolone and imidazolone or salts thereof, and pharmaceutical compositions containing the same | 柳韩洋行 | 2023-12-08 | — | — | CN | disclosed |