Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3065900 | 0.71 | USP30 (0.49) | MCHR1UTS2RCHRM4USP30 | |
| SCHEMBL3063005 | 0.71 | SPR (0.39) | HTTSMPD3PIM1MEN1KMT2A | |
| SCHEMBL4970792 | 0.71 | MCHR1 (0.55) | MCHR1UTS2RSMYD3PIM1KDM4E | |
| SCHEMBL3060481 | 0.68 | MCHR1 (0.48) | MCHR1UTS2RALDH1A1HPGDHSD17B10 | |
| SCHEMBL4955202 | 0.68 | DRD4 (0.39) | HTTSMPD3MEN1KMT2AALDH1A1 | |
| SCHEMBL27124836 | 0.68 | MCHR1 (0.50) | MCHR1UTS2RPRKDCKDM4ENPC1 | |
| SCHEMBL3068444 | 0.67 | ADRB2 (0.48) | MCHR1UTS2RPRKDCSMYD3 | |
| SCHEMBL2554945 | 0.67 | RAB9A (0.52) | MCHR1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28264042 | 0.67 | RAB9A (0.52) | MCHR1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3061487 | 0.67 | MCHR1 (0.44) | MCHR1UTS2RPRKDCALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267717-A1 | Novel Heterocyclic NF-kB Inhibitors | 4SC AG (DE) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267717-A1 | Novel Heterocyclic NF-kB Inhibitors | NFKB2, NFKBIA, NFRKB | MCHR1 3580/4885UTS2R 836/4885CFTR 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.