Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26118448 | 1.00 | CASP3 (0.51) | CASP3MAPK1MAOBTDP1L3MBTL1 | |
| SCHEMBL8109703 | 0.77 | TDP1 (0.57) | CASP3MAOBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29596524 | 0.76 | KEAP1 (0.60) | CASP3MAOBALDH1A1MAPTNPSR1 | |
| SCHEMBL7524646 | 0.76 | KEAP1 (0.60) | CASP3MAOBALDH1A1MAPTNPSR1 | |
| SCHEMBL7215474 | 0.75 | CASP3 (0.50) | CASP3MAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL31664133 | 0.75 | MAPK1 (0.53) | CASP3MAPK1MAOBTDP1L3MBTL1 | |
| SCHEMBL21070307 | 0.75 | MAPK1 (0.53) | CASP3MAPK1MAOBTDP1L3MBTL1 | |
| SCHEMBL19985874 | 0.75 | MAOB (0.49) | MAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21070623 | 0.75 | ALDH1A1 (0.48) | CASP3MAOBL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30630014 | 0.75 | ALDH1A1 (0.48) | CASP3MAOBL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504179-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | Corbus Pharmaceuticals, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-119325378-A | Cannabinoid receptor 1 antagonists/inverse agonists and uses thereof | 柯巴斯医药有限公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023196556-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |