Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566000 | 0.86 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL560256 | 0.86 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16474055 | 0.84 | MAPT (0.51) | MAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11878793 | 0.81 | MAOB (0.54) | MAOB | |
| SCHEMBL12632010 | 0.81 | KMT2A (0.46) | RAB9A | |
| SCHEMBL1787317 | 0.80 | MAOB (0.56) | MAOB | |
| SCHEMBL10204012 | 0.80 | RAB9A (0.48) | MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6430052 | 0.80 | MAOB (0.52) | MAOB | |
| SCHEMBL7338729 | 0.80 | ALDH1A1 (0.48) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27203457 | 0.79 | NPC1 (0.48) | MAOBMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | MAOB 127/4885MAPT 4276/4885RAB9A 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.