Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632963 | 0.79 | NFE2L2 (0.55) | NFKB1NFE2L2RAB9A | |
| SCHEMBL30632929 | 0.76 | MAPT (0.53) | NFKB1NFE2L2RAB9A | |
| SCHEMBL30632983 | 0.74 | NAPRT (0.36) | NFE2L2RAB9A | |
| SCHEMBL15870902 | 0.73 | — | — | |
| SCHEMBL28473621 | 0.72 | CYP1A1 (0.37) | NFE2L2BACE1 | |
| SCHEMBL29937227 | 0.71 | AHR (0.45) | — | |
| SCHEMBL2278846 | 0.71 | GRM4 (0.44) | NFE2L2RAB9AMAOB | |
| SCHEMBL2278845 | 0.71 | GRM4 (0.44) | NFE2L2RAB9AMAOB | |
| SCHEMBL6593788 | 0.70 | TNF (0.48) | NFKB1LMNANFE2L2TNFRAB9A | |
| SCHEMBL6593793 | 0.70 | TNF (0.48) | NFKB1LMNANFE2L2TNFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |