Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486928 | 0.82 | NAPRT (0.48) | NAPRTKDM4EGRM4NFE2L2NPC1 | |
| SCHEMBL8486922 | 0.82 | NAPRT (0.48) | NAPRTKDM4EGRM4NFE2L2NPC1 | |
| SCHEMBL30632963 | 0.81 | NFE2L2 (0.55) | KDM4EGRM4NFE2L2NPC1PKM | |
| SCHEMBL30632910 | 0.77 | NFE2L2 (0.44) | KDM4ENFE2L2 | |
| SCHEMBL15870902 | 0.75 | — | — | |
| SCHEMBL30632929 | 0.75 | MAPT (0.53) | KDM4ENFE2L2NPC1MAPTPKM | |
| SCHEMBL30632909 | 0.74 | NFKB1 (0.45) | NFE2L2RAB9A | |
| SCHEMBL30632951 | 0.72 | NFE2L2 (0.44) | KDM4ENFE2L2NPC1MAPTRAB9A | |
| SCHEMBL15870877 | 0.72 | MEN1 (0.30) | NPC1RAB9A | |
| SCHEMBL30632897 | 0.72 | NFE2L2 (0.50) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |