Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632983 | 0.81 | NAPRT (0.36) | NFE2L2GRM4KDM4ENPC1PKM | |
| SCHEMBL30632951 | 0.81 | NFE2L2 (0.44) | NFE2L2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30632906 | 0.80 | NUDT1 (0.36) | NFE2L2GRM4 | |
| SCHEMBL30632897 | 0.80 | NFE2L2 (0.50) | NFE2L2HTR2A | |
| SCHEMBL30632929 | 0.79 | MAPT (0.53) | NFE2L2KDM4ERELANPC1PKM | |
| SCHEMBL30632909 | 0.79 | NFKB1 (0.45) | NFE2L2NFKB1RAB9A | |
| SCHEMBL30632910 | 0.78 | NFE2L2 (0.44) | NFE2L2KDM4E | |
| SCHEMBL30633073 | 0.78 | NPC1 (0.36) | NFE2L2KDM4ENPC1PKMRAB9A | |
| SCHEMBL30632943 | 0.78 | NFE2L2 (0.33) | NFE2L2GRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15870902 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |