Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640449 | 0.82 | MAPT (0.60) | RAB9AMAPTNPC1SMN1; SMN2FBP1 | |
| SCHEMBL18640452 | 0.82 | MAPT (0.60) | RAB9AMAPTNPC1SMN1; SMN2FBP1 | |
| SCHEMBL30633018 | 0.82 | MAPT (0.60) | RAB9AMAPTNPC1SMN1; SMN2FBP1 | |
| SCHEMBL30632879 | 0.77 | ALDH1A1 (0.39) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL14947048 | 0.77 | APP (0.78) | RAB9AMAPTNPC1PTGS2APP | |
| SCHEMBL458177 | 0.77 | APP (0.78) | RAB9AMAPTNPC1PTGS2APP | |
| SCHEMBL9170800 | 0.77 | APP (0.78) | RAB9AMAPTNPC1PTGS2APP | |
| SCHEMBL9170804 | 0.77 | APP (0.78) | RAB9AMAPTNPC1PTGS2APP | |
| SCHEMBL458178 | 0.77 | APP (0.78) | RAB9AMAPTNPC1PTGS2APP | |
| SCHEMBL11133083 | 0.77 | MAPT (0.61) | RAB9AMAPTNPC1PTGS2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |