Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949356 | 1.00 | ADORA3 (0.39) | ADORA3TMEM97SIGMAR1DRD3ADORA2A | |
| SCHEMBL1917392 | 0.94 | ADORA3 (0.39) | ADORA3TMEM97SIGMAR1DRD3DAO | |
| SCHEMBL27035392 | 0.87 | CDK9 (0.35) | ADORA3TMEM97SIGMAR1DAOAXL | |
| SCHEMBL3949234 | 0.83 | TSPO (0.38) | ADORA3TMEM97DRD3ADORA2AADORA1 | |
| SCHEMBL3949386 | 0.81 | BRD4 (0.40) | ADORA3ADORA2AADORA1NOS1NOS2 | |
| SCHEMBL3948904 | 0.81 | PDK2 (0.37) | ADORA3TMEM97DRD3ADORA2AADORA1 | |
| SCHEMBL3952077 | 0.81 | MAPT (0.38) | ADORA3TMEM97DRD3ADORA2AADORA1 | |
| SCHEMBL3952234 | 0.81 | ADORA3 (0.36) | ADORA3TMEM97DRD3ADORA2AADORA1 | |
| SCHEMBL17645940 | 0.79 | DAO (0.36) | DAO | |
| SCHEMBL3957784 | 0.78 | ADORA2B (0.35) | ADORA3ADORA2AADORA1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |