Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017939 | 1.00 | GAA (0.35) | GAAMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL27083571 | 0.82 | DAO (0.33) | — | |
| SCHEMBL23528853 | 0.82 | DAO (0.33) | — | |
| SCHEMBL13401017 | 0.82 | CYP3A4 (0.33) | GAAMAPTALDH1A1 | |
| SCHEMBL27449232 | 0.76 | GABRA1 (0.38) | GAAMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL21393521 | 0.73 | CES2 (0.34) | — | |
| SCHEMBL1194575 | 0.73 | CHRNB4 (0.36) | — | |
| SCHEMBL2016306 | 0.73 | — | — | |
| SCHEMBL219619 | 0.73 | — | — | |
| SCHEMBL11798292 | 0.71 | ALDH1A1 (0.57) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043162-A | TYK2 selective inhibitors and uses thereof | 迈巴制药(南京)有限公司 | 2023-11-10 | — | — | CN | disclosed |