Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730228 | 0.87 | GRM5 (0.33) | RAB9AGRM5ALDH1A1HPGDMEN1 | |
| SCHEMBL24618229 | 0.84 | OPRM1 (0.45) | CYP1A2 | |
| SCHEMBL12592990 | 0.83 | RAB9A (0.41) | RAB9AGRM5ALDH1A1HPGDMEN1 | |
| SCHEMBL23089691 | 0.82 | ATM (0.47) | LMNAHSD11B1 | |
| SCHEMBL29736610 | 0.82 | ATM (0.47) | LMNAHSD11B1 | |
| SCHEMBL9988608 | 0.81 | GRM5 (0.35) | RAB9AGRM5ALDH1A1HPGDMEN1 | |
| SCHEMBL19583840 | 0.81 | ALDH1A1 (0.43) | RAB9AGRM5ALDH1A1HPGDMEN1 | |
| SCHEMBL9989158 | 0.80 | AKR1C1 (0.39) | GRM5ALDH1A1HPGDKDM4EHSD11B1 | |
| SCHEMBL9988917 | 0.79 | OPRM1 (0.34) | GRM5ALDH1A1HPGDGAAPOLB | |
| SCHEMBL9988689 | 0.78 | LMNA (0.36) | GRM5ALDH1A1HPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043162-A | TYK2 selective inhibitors and uses thereof | 迈巴制药(南京)有限公司 | 2023-11-10 | — | — | CN | disclosed |