Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21469774 | 0.84 | MAPT (0.43) | AKR1C3MAPTKDM4EALDH1A1PKM | |
| SCHEMBL24269934 | 0.84 | MAPT (0.46) | MAPTKDM4EALDH1A1PKMTSHR | |
| SCHEMBL12865183 | 0.83 | LMNA (0.51) | AKR1C3MAPTKDM4EALDH1A1PKM | |
| SCHEMBL21464505 | 0.82 | PKM (0.63) | MAPTKDM4EALDH1A1PKMTSHR | |
| SCHEMBL1172898 | 0.81 | AKR1C3 (0.47) | AKR1C3MAPTPKMTSHRPIK3CA | |
| SCHEMBL21464158 | 0.80 | PKM (0.68) | ALDH1A1PKMTSHRMEN1KMT2A | |
| SCHEMBL1172676 | 0.80 | SLC6A9 (0.54) | AKR1C3MAPTALDH1A1PKMTSHR | |
| SCHEMBL24270121 | 0.79 | KDM4E (0.50) | AKR1C3MAPTKDM4EALDH1A1TSHR | |
| SCHEMBL30633561 | 0.78 | MET (0.45) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21464585 | 0.77 | PIK3CA (0.61) | PIK3CAAKT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043162-A | TYK2 selective inhibitors and uses thereof | 迈巴制药(南京)有限公司 | 2023-11-10 | — | — | CN | disclosed |