Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137883 | 0.77 | TAAR1 (0.54) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL28019453 | 0.74 | TAAR1 (0.50) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL7435206 | 0.72 | CYP3A4 (0.59) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL13151044 | 0.71 | TAAR1 (0.47) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9680094 | 0.71 | KCNN4 (0.40) | TAAR1LMNACYP2D6CYP2C19CYP3A4 | |
| SCHEMBL31468672 | 0.71 | LMNA (0.48) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| SCHEMBL7078495 | 0.69 | ALDH1A1 (0.54) | TAAR1SLC6A2LMNATSHRCYP3A4 | |
| SCHEMBL9427318 | 0.69 | SLC6A2 (0.54) | TAAR1SLC6A2LMNACYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL27661297 | 0.68 | ALDH1A1 (0.52) | TAAR1SLC6A2LMNATSHRCYP3A4 | |
| SCHEMBL21353 | 0.68 | SLC6A2 (0.58) | TAAR1SLC6A2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279887-A | Inhibitors and uses thereof | 纽洛可科学有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116981946-A | LRRC4 family mimic molecules and diagnostic uses thereof | 纽洛可科学有限公司 | 2023-10-31 | — | — | CN | disclosed |