Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SCN1A | P35498 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.59 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435200 | 0.84 | CYP3A4 (0.57) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| SCHEMBL9234745 | 0.81 | KMT2A (0.62) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| Acetic Acid SCHEMBL1551090 | 0.76 | HIF1A (0.50) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| SCHEMBL6137883 | 0.76 | TAAR1 (0.54) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| Oxethazaine SCHEMBL24489 | 0.75 | KMT2A (1.00) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| Oxethazaine SCHEMBL4280369 | 0.75 | KMT2A (1.00) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| SCHEMBL424806 | 0.74 | HIF1A (0.48) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| Oxethazaine SCHEMBL945710 | 0.74 | MEN1 (0.97) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| SCHEMBL31468672 | 0.73 | LMNA (0.48) | CYP3A4CYP2C19HIF1ALMNACYP2D6 | |
| SCHEMBL28074949 | 0.73 | CYP3A4 (0.47) | CYP3A4CYP2C19HIF1ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1141089-C | Antimicrobials | ������������ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| EP-0702013-B1 | Imidazopyridines | MERCK PATENT GMBH (DE) | 2001-06-13 | — | — | EP | disclosed |
| CN-1270517-A | Antimicrobials | EISAI CO LTD (JP) | 2000-10-18 | — | — | CN | disclosed |
| US-5684015-A | ANGIOTENSIN ANTAGONIST AS HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-11-04 | — | — | US | disclosed |
| EP-0702013-A2 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1996-03-20 | — | — | EP | disclosed |
| US-5476857-A | Imidazopyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-19 | — | — | US | disclosed |
| US-5438063-A | Hypotensive agents, cardiac insufficiency, increased intraocular pressure, and CNS disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0657454-A1 | Imidazopyridazines being angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0628556-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0574846-A2 | Imidazopyridines as angiotensin II antagonistes | MERCK PATENT GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |