Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750523 | 1.00 | KDM4E (0.39) | KDM4EPRMT6EPHX2SMN1; SMN2NOS1 | |
| SCHEMBL3665839 | 0.89 | PRMT6 (0.45) | KDM4EPRMT6EPHX2SMN1; SMN2NOS1 | |
| SCHEMBL15301629 | 0.80 | KDM4E (0.41) | KDM4ESMN1; SMN2MAPTHTTDYRK1A | |
| SCHEMBL27784845 | 0.79 | KDM4E (0.43) | KDM4ESMN1; SMN2MAPTHTTDYRK1A | |
| SCHEMBL19417587 | 0.79 | KDM4E (0.36) | KDM4ESMN1; SMN2MAPTHTTDYRK1A | |
| SCHEMBL3669053 | 0.78 | NOS1 (0.49) | KDM4EPRMT6EPHX2SMN1; SMN2NOS1 | |
| SCHEMBL21535264 | 0.77 | PKM (0.40) | KDM4ESMN1; SMN2MAPTHTTDYRK1A | |
| SCHEMBL10061636 | 0.77 | CYP11B1 (0.43) | PRMT6EPHX2NOS1NOS2CYP3A4 | |
| SCHEMBL13771813 | 0.77 | PRMT6 (0.40) | KDM4EPRMT6EPHX2NOS1MAPT | |
| SCHEMBL3711569 | 0.76 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304095-B | N-aryl-N-arpropargyl-aromatic acetamide compound and pharmaceutical application thereof | ZHEJIANG UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| EP-4514788-A1 | NITROGEN COMPRISING HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH GPR55 RECEPTOR | Cerevance, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-112135821-B | 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors | 方济各安吉利克化学联合股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117304095-A | N-aryl-N-arpropargyl-aromatic acetamide compound and pharmaceutical application thereof | 浙江大学 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023209368-A1 | NITROGEN COMPRISING HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH GPR55 RECEPTOR | Cerevance, Inc. (US) | 2023-11-02 | — | — | WO | disclosed |