Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511565 | 1.00 | PIK3CD (0.44) | PIK3CDMAP4K4MKNK1MKNK2MAPT | |
| SCHEMBL30269910 | 0.83 | PIK3CD (0.51) | PIK3CDMAP4K4MKNK1MKNK2MAPT | |
| SCHEMBL22164604 | 0.83 | PIK3CD (0.51) | PIK3CDMAP4K4MKNK1MKNK2MAPT | |
| SCHEMBL18520105 | 0.81 | ALDH1A1 (0.41) | PIK3CDMAPTPIK3CAPIK3CGALOX5AP | |
| SCHEMBL30695445 | 0.79 | DYRK1A (0.45) | PIK3CDPIK3CAPIK3CGPIP5K1CPI4KA | |
| SCHEMBL20409478 | 0.74 | PIK3CD (0.48) | PIK3CDMAP4K4MKNK1MKNK2MAPT | |
| SCHEMBL3387141 | 0.74 | KIT (0.56) | PIK3CDMAP4K4MKNK1MKNK2MAPT | |
| SCHEMBL17809810 | 0.74 | CREBBP (0.39) | PIK3CDMAPTPIK3CAPIK3CGPIP5K1C | |
| SCHEMBL30888279 | 0.73 | ALDH1A1 (0.52) | PIK3CDMAPTPIK3CAPIK3CGKCNH2 | |
| SCHEMBL1257460 | 0.73 | PIK3CD (0.73) | PIK3CDMAP4K4MKNK1MKNK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |