Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17840873 | 1.00 | KDM4E (0.44) | KDM4EHSD17B10CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1841951 | 0.85 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL29522769 | 0.85 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL17840704 | 0.85 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL536169 | 0.83 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL26674519 | 0.77 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31437236 | 0.77 | ALDH1A1 (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31330687 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL535620 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1GAAMAPK1SMN1; SMN2 | |
| SCHEMBL25246581 | 0.76 | SMN1; SMN2 (0.47) | KDM4ECYP4F2CYP4A11ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894872-A | Heteroarenes, pharmaceutical compositions containing heteroarenes, and methods of use thereof | 修复治疗公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-4526293-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | Repare Therapeutics Inc. (CA) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023220831-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | REPARE THERAPEUTICS INC. (CA) | 2023-11-23 | — | — | WO | disclosed |