Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860050 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHTTDRD2 | |
| SCHEMBL26597140 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAHTTDRD2 | |
| SCHEMBL12459066 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL26597118 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL26597125 | 0.81 | LMNA (0.47) | ALDH1A1MAPTLMNADRD2SMN1; SMN2 | |
| SCHEMBL31543863 | 0.81 | LMNA (0.47) | ALDH1A1MAPTLMNADRD2SMN1; SMN2 | |
| SCHEMBL2731653 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL499984 | 0.80 | MAPT (0.50) | ALDH1A1MAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL17181346 | 0.80 | MAPT (0.50) | ALDH1A1MAPTLMNACYP1A2CYP2D6 | |
| SCHEMBL31333796 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | Shenzhen Sungening Biological Co., Ltd (CN) | 2024-10-03 | — | — | US | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | DHODH, PPOX, HPD | ALDH1A1 575/4885MAPT 1443/4885LMNA 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.