Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydroxyurea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyurea SCHEMBL4004 | 0.95 | — | — | |
| Hydroxyurea SCHEMBL93814 | 0.95 | LMNA (1.00) | — | |
| Hydroxyurea SCHEMBL5329855 | 0.95 | LMNA (1.00) | — | |
| Hydroxyurea SCHEMBL308240 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28164447 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL23274911 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL27583606 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28783824 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL15011410 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28868410 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381289-B1 | COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND | BAYER CROPSCIENCE LP (US) | 2021-05-05 | — | — | EP | claimed |
| EP-2292098-B1 | Combinations comprising a fungicidal strain and at least one additional fungicide | BAYER CROPSCIENCE LP (US) | 2019-11-06 | — | — | EP | claimed |
| EP-3510869-A1 | COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND | Bayer Cropscience LP (US) | 2019-07-17 | — | — | EP | claimed |
| EP-3381289-A1 | COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND | Bayer Cropscience LP (US) | 2018-10-03 | — | — | EP | claimed |
| US-20170318816-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2017-11-09 | — | — | US | claimed |
| US-9743674-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2017-08-29 | — | — | US | claimed |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2016-10-13 | — | — | US | claimed |
| US-9392797-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2016-07-19 | — | — | US | claimed |
| US-20150264939-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2015-09-24 | — | — | US | claimed |
| US-9078447-B2 | Combinations comprising a fungicidal strain and an active compound | BAYER CROPSCIENCE LP (US) | 2015-07-14 | — | — | US | claimed |
| WO-2009062905-A1 | PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| US-20090123561-A1 | Fungicide mixtures based on 1-methyl-pyrazol-4-ylcarboxanilides | BASF AKTIENGESELLLSCHAFT (DE) | 2009-05-14 | — | — | US | claimed |
| WO-2009040397-A1 | TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL | BASF SE (DE) | 2009-04-02 | — | — | WO | claimed |
| WO-2009037242-A2 | COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND | BASF SE (DE) | 2009-03-26 | — | — | WO | claimed |
| US-20090042725-A1 | Fungicidal Mixtures Based on 3,5-Disubstituted N-Biphenyl-Pyrazolcarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | claimed |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | claimed |
| WO-2009007233-A2 | PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES | BASF SE (DE) | 2009-01-15 | — | — | WO | claimed |
| US-20080293798-A1 | Fungicidal Mixtures Comprising Substituted 1-Methylpyrazol-4-Ylcarboxanilides | BASF AKTIENGELSELLSCHAFT (DE) | 2008-11-27 | — | — | US | claimed |
| US-20080255107-A1 | Fungicidal Mixtures Comprising N-[2-(Haloalk(Enyl)Oxy)Phenyl]Carboxamides | BASF SE (DE) | 2008-10-16 | — | — | US | claimed |
| WO-2008095890-A2 | FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES | BASF SE (DE) | 2008-08-14 | — | — | WO | claimed |