Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydroxyurea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyurea SCHEMBL7942158 | 0.96 | — | — | |
| Hydroxyurea SCHEMBL5329855 | 0.95 | LMNA (1.00) | — | |
| Hydroxyurea SCHEMBL93814 | 0.95 | LMNA (1.00) | — | |
| Hydroxyurea SCHEMBL4004 | 0.95 | — | — | |
| Hydroxyurea SCHEMBL23274911 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL306433 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28783824 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28868410 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL28164447 | 0.91 | — | — | |
| Hydroxyurea SCHEMBL15011410 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027894-A | Adhesive, negative electrode slurry and lithium ion battery | 深圳好电科技有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118027894-A | Adhesive, negative electrode slurry and lithium ion battery | 深圳好电科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114651004-A | Novel interleukin-2 variants for cancer treatment | 科优基因公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-104653259-B | Exhaust gas aftertreatment | 沃尔沃汽车公司 | 2019-08-27 | — | — | CN | disclosed |
| US-8093176-B2 | Process for the continuous production of catalysts | BAYER MATERIALSCIENCE AG (DE) | 2012-01-10 | — | — | US | disclosed |
| US-20080003169-A1 | PROCESS FOR THE CONTINUOUS PRODUCTION OF CATALYSTS | BAYER MATERIALSCIENCE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-4398036-A | FROM AROMATIC AMINE, ALKALOL LAND UREA IN PRESENCE OF TERTIARY AMINE CATALYST | ATLANTIC RICHFIELD COMPANY (US) | 1983-08-09 | — | — | US | disclosed |