Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26690858 | 0.87 | ALDH1A1 (0.42) | ACRALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL26690754 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL26690705 | 0.75 | ALDH1A1 (0.42) | ACRALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL30181119 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL966496 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2835446 | 0.71 | TSHR (0.44) | ALDH1A1MAPTL3MBTL1MEN1NPC1 | |
| SCHEMBL29775653 | 0.70 | L3MBTL1 (0.47) | ACRALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL21047410 | 0.70 | L3MBTL1 (0.47) | ACRALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL31579039 | 0.70 | RAB9A (0.45) | ALDH1A1MAPTMEN1NPC1KMT2A | |
| SCHEMBL31579139 | 0.69 | EGLN1 (0.43) | ALDH1A1MAPTL3MBTL1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514782-A1 | AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | Astrazeneca AB (SE) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023222850-A1 | AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES | ASTRAZENECA AB (SE) | 2023-11-23 | — | — | WO | disclosed |