Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26667209 | 1.00 | HPN (0.60) | HPNCCR6ALDH1A1MAPTPKM | |
| SCHEMBL10587599 | 0.89 | HPN (0.68) | HPNCCR6ALDH1A1MAPTPKM | |
| SCHEMBL17044675 | 0.89 | HPN (0.68) | HPNCCR6ALDH1A1MAPTPKM | |
| SCHEMBL5078820 | 0.78 | MGLL (0.62) | CCR6ALDH1A1MAPTPKMMAPK1 | |
| SCHEMBL3171879 | 0.78 | MGLL (0.62) | CCR6ALDH1A1MAPTPKMMAPK1 | |
| Nitrogen SCHEMBL9840130 | 0.76 | CYP19A1 (0.56) | ALDH1A1MAPK1TDP1HTTTSHR | |
| SCHEMBL204235 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPK1TDP1HTTTSHR | |
| SCHEMBL1943699 | 0.76 | CYP19A1 (0.62) | ALDH1A1MAPK1TDP1HTTTSHR | |
| SCHEMBL2029909 | 0.75 | HPN (1.00) | HPNALDH1A1MAPTPKMGAA | |
| SCHEMBL30532190 | 0.75 | HPN (1.00) | HPNALDH1A1MAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525864-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | Emory University (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225300-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |