Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700016 | 0.83 | CCR1 (0.53) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL3467288 | 0.81 | CCR1 (0.52) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL1827524 | 0.81 | NFE2L2 (0.57) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL30646276 | 0.81 | CA2 (0.41) | NOS3NOS1NOS2NFE2L2CA2 | |
| SCHEMBL27326954 | 0.80 | NFE2L2 (0.50) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL30845679 | 0.75 | KDM4E (0.48) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL3675739 | 0.75 | KDM4E (0.48) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL31527805 | 0.73 | KDM4E (0.47) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL18007585 | 0.73 | KDM4E (0.54) | CA2 | |
| SCHEMBL12061378 | 0.72 | CA2 (0.50) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062817-A | Pyrazolo [3,4-D ] pyrimidin-6-yl-sulfonamide derivatives for SGK-1 inhibition | 斯瑞福治疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |