Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648402 | 0.80 | CYP11B1 (0.49) | HTTKIF11ALDH1A1LMNACYP11B1 | |
| SCHEMBL30648382 | 0.77 | CYP11B1 (0.44) | HTTKIF11ALDH1A1LMNACYP11B1 | |
| SCHEMBL30648398 | 0.73 | KIF11 (0.46) | HTTKIF11ALDH1A1LMNACYP11B1 | |
| SCHEMBL10651353 | 0.71 | KIF11 (0.58) | HTTKIF11ALDH1A1LMNAEPHX2 | |
| SCHEMBL4296023 | 0.70 | NR3C2 (0.66) | — | |
| SCHEMBL30648390 | 0.69 | ALDH1A1 (0.44) | HTTKIF11ALDH1A1LMNACYP11B1 | |
| SCHEMBL4297311 | 0.69 | NR3C2 (0.69) | — | |
| SCHEMBL4258367 | 0.69 | HTT (0.59) | HTTALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL4748346 | 0.67 | DHFR (0.46) | HTTALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL10509516 | 0.66 | HTT (0.59) | HTTALDH1A1LMNACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947846-B | Parallel ring derivative and preparation method and application thereof | 成都硕德药业有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-116947846-A | Parallel ring derivative and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |