SCHEMBL30648593

SCHEMBL30648593

C=C[C@@H](CSc1ccccc1)[C@@H](O)c1ccc(SC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
MTNR1A P48039 3/20 0.35
MTNR1B P49286 3/20 0.35
SLC6A4 P31645 2/20 0.34
KIF11 P52732 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648565 0.88 MAOA (0.41) KDM4EMAOAMAOBMTNR1AMTNR1B
SCHEMBL29155614 0.87 MAOA (0.39) MAOAMAOBMEN1KMT2AMTNR1A
SCHEMBL29155615 0.87 MAOA (0.39) MAOAMAOBMEN1KMT2AMTNR1A
SCHEMBL30648577 0.86 CYP3A4 (0.39) MAOAMAOBMTNR1AMTNR1BSLC6A4
SCHEMBL30648596 0.84 MAPT (0.40) KDM4EMAOAMAOBMTNR1AMTNR1B
SCHEMBL30648575 0.84 MMP2 (0.40) MAOAMAOBMEN1KMT2AMTNR1A
SCHEMBL30648590 0.84 ALDH1A1 (0.40) MAOAMAOBSLC6A4ALDH1A1LMNA
SCHEMBL30648578 0.80 TSHR (0.47) KDM4EMEN1KMT2AMTNR1AMTNR1B
SCHEMBL30648599 0.74 MAOA (0.42) MAOAMAOBMTNR1AMTNR1BSLC6A4
SCHEMBL30648581 0.73 TSHR (0.36) MAOAMAOBMEN1KMT2AMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304081-A Method for synthesizing homoallylic alcohol compound by synergistic catalysis of visible light and titanium 河南师范大学 2023-12-29 CN disclosed