Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
| ▸ | GABRE | P78334 | 1/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709826 | 0.77 | CA5A (0.56) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10376053 | 0.74 | GABRP (0.54) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15724493 | 0.72 | ALDH1A1 (0.45) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL18889768 | 0.72 | NPC1 (0.53) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30293720 | 0.72 | KDM4E (0.52) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31219105 | 0.72 | KDM4E (0.49) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7036195 | 0.72 | KDM4E (0.62) | KMT2AKDM4ELMNATDP1MGAM | |
| SCHEMBL31219222 | 0.72 | NPC1 (0.53) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Carbazole SCHEMBL8411559 | 0.71 | ALDH1A1 (0.74) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| Carbazole SCHEMBL27864756 | 0.71 | LMNA (0.69) | KMT2AGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273150-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | The National Institutes of Pharmaceutical R&D Co., Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |