Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20821383 | 0.70 | GPR3 (0.42) | TERTDAOSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL29354440 | 0.69 | SMN1; SMN2 (0.39) | TERTDAOSMN1; SMN2PBRM1L3MBTL1 | |
| SCHEMBL4510784 | 0.69 | SMN1; SMN2 (0.39) | TERTDAOSMN1; SMN2PBRM1L3MBTL1 | |
| SCHEMBL16050180 | 0.69 | ENPP3 (0.41) | TERTSMN1; SMN2L3MBTL1TRPM4KMT2A | |
| SCHEMBL31116733 | 0.69 | ENPP3 (0.41) | TERTSMN1; SMN2L3MBTL1TRPM4KMT2A | |
| SCHEMBL3547426 | 0.67 | KDM4E (0.49) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6786929 | 0.66 | KDM4E (0.44) | SMN1; SMN2PBRM1L3MBTL1KMT2AMEN1 | |
| SCHEMBL143866 | 0.64 | CDC25B (0.37) | TERTDAOSMN1; SMN2PBRM1L3MBTL1 | |
| SCHEMBL18069003 | 0.64 | ENPP3 (0.38) | TERTSMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL18025278 | 0.63 | KDM4E (0.42) | TERTSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |