Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 16/20 | 0.40 |
| ▸ | CDK9 | P50750 | 16/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 4/20 | 0.36 |
| ▸ | CCND1 | P24385 | 4/20 | 0.36 |
| ▸ | CDK7 | P50613 | 3/20 | 0.36 |
| ▸ | CCNH | P51946 | 3/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878728 | 0.79 | PIK3CD (0.38) | PIK3CDPIK3R1CCNT1CDK9KCNN3 | |
| SCHEMBL20484514 | 0.76 | DGAT1 (0.36) | PIK3CDPIK3R1CCNT1CDK9KCNN3 | |
| SCHEMBL14564413 | 0.75 | KCNN3 (0.40) | PIK3CDPIK3R1CCNT1CDK9KCNN3 | |
| SCHEMBL14158215 | 0.73 | KCNN3 (0.71) | CCNT1CDK9KCNN3CDK2 | |
| SCHEMBL4569211 | 0.72 | DGAT1 (0.43) | PIK3CDPIK3R1CCNT1CDK9KCNN3 | |
| SCHEMBL11962829 | 0.71 | KDM4E (0.49) | CDK2LRRK2 | |
| SCHEMBL12258899 | 0.71 | OXTR (0.41) | LRRK2 | |
| SCHEMBL11568710 | 0.70 | PIK3CD (0.37) | PIK3CDPIK3R1CCNT1CDK9KCNN3 | |
| SCHEMBL2034177 | 0.70 | CDK9 (0.52) | CCNT1CDK9CDK4CCND1CDK7 | |
| SCHEMBL22971391 | 0.70 | KCNH2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |