Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.30 |
| ▸ | TUBB | P07437 | 3/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839001 | 0.92 | CYP3A4 (0.37) | CYP3A4CYP2C9TUBB4ATUBBTUBA3C | |
| SCHEMBL3062417 | 0.92 | HDAC3 (0.32) | CYP3A4STAT3HDAC3TUBB4ATUBB | |
| SCHEMBL3062421 | 0.92 | HDAC3 (0.32) | CYP3A4STAT3HDAC3TUBB4ATUBB | |
| SCHEMBL2844861 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL2842877 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL2844825 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL2842826 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL2840110 | 0.91 | HDAC3 (0.31) | STAT3HDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL2849386 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 | |
| SCHEMBL2841087 | 0.91 | MAOA (0.38) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222302-A1 | Novel Antibacterial Compounds | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222302-A1 | Novel Antibacterial Compounds | ODC1, AOC1, OGFOD1 | CYP3A4 1420/4885CYP2C9 1272/4885STAT3 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.