SCHEMBL30656118

SCHEMBL30656118

Cc1ncsc1COc1ccc2sc(C)c(C(=O)NC3(C(N)=O)CCOCC3)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.37
MMP3 P08254 2/20 0.33
MMP7 P09237 2/20 0.33
ADAMTS4 O75173 1/20 0.33
ADAM17 P78536 1/20 0.33
ADAMTS1 Q9UHI8 1/20 0.33
ADAMTS5 Q9UNA0 1/20 0.33
MMP13 P45452 3/20 0.31
MMP1 P03956 2/20 0.31
MMP2 P08253 1/20 0.31
MMP12 P39900 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
OPRL1 P41146 1/20 0.31
EGLN2 Q96KS0 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
PARP15 Q460N3 1/20 0.30
PARP10 Q53GL7 1/20 0.30
PDE5A O76074 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30655967 0.92 PARP15 (0.31) PARP15PARP10
SCHEMBL30656018 0.88 ADAM17 (0.38) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL29630169 0.86 GAA (0.43)
SCHEMBL30656207 0.85 CNR2 (0.38) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656215 0.84 MAPK14 (0.39) CNR2CYP4F2CYP4A11PARP10
SCHEMBL30655952 0.83 ADAM17 (0.32) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656026 0.83 SCN9A (0.33) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656111 0.82 MMP1 (0.46) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656350 0.81 ADAM17 (0.34) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL24485383 0.81 GAA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed