SCHEMBL30656207

SCHEMBL30656207

Cc1ncc(COc2ccc3sc(C)c(C(=O)NC4(C(N)=O)CCOCC4)c3c2)s1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.38
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
MMP3 P08254 2/20 0.33
MMP7 P09237 2/20 0.33
ADAMTS4 O75173 1/20 0.33
ADAM17 P78536 1/20 0.33
ADAMTS1 Q9UHI8 1/20 0.33
ADAMTS5 Q9UNA0 1/20 0.33
MMP13 P45452 2/20 0.32
MMP1 P03956 1/20 0.32
DPP4 P27487 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRL1 P41146 2/20 0.31
MMP2 P08253 1/20 0.30
MMP12 P39900 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656261 0.95 CNR2 (0.34) CNR2CYP4F2CYP4A11MMP3MMP7
SCHEMBL30656075 0.91 L3MBTL1 (0.32) CNR2L3MBTL1
SCHEMBL30656155 0.88 CCNE1 (0.32) CYP4F2CYP4A11MMP3MMP7ADAMTS4
SCHEMBL30656102 0.87 MMP3 (0.38) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656215 0.85 MAPK14 (0.39) CNR2CYP4F2CYP4A11
SCHEMBL30656118 0.85 CNR2 (0.37) CNR2CYP4F2CYP4A11MMP3MMP7
SCHEMBL30656111 0.83 MMP1 (0.46) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656263 0.83 L3MBTL1 (0.34) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656220 0.82 L3MBTL1 (0.33) CNR2MMP3MMP7ADAMTS4ADAM17
SCHEMBL30656104 0.82 ABL1 (0.36) CNR2ADAM17L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed