SCHEMBL30656121

SCHEMBL30656121

Cc1sc2ccc(OCc3cccnc3O)cc2c1C(=O)NC1(CO)CCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.38
ADAM17 P78536 6/20 0.36
CD274 Q9NZQ7 3/20 0.35
ANO1 Q5XXA6 1/20 0.33
ABL1 P00519 1/20 0.33
ADAMTS4 O75173 2/20 0.33
MMP3 P08254 2/20 0.33
MMP7 P09237 2/20 0.33
ADAMTS1 Q9UHI8 2/20 0.33
ADAMTS5 Q9UNA0 2/20 0.33
MMP8 P22894 1/20 0.33
EGLN2 Q96KS0 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
CNR1 P21554 2/20 0.33
KMT2A Q03164 1/20 0.32
SLC26A4 O43511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656274 0.93 ADAM17 (0.41) CNR2ADAM17CD274ANO1ADAMTS4
SCHEMBL30656330 0.90 CD274 (0.37) CNR2ADAM17CD274ABL1ADAMTS4
SCHEMBL30656112 0.86 CD274 (0.35) CNR2ADAM17CD274ADAMTS4MMP3
SCHEMBL30656091 0.86 PARP15 (0.39) ADAM17CD274KMT2A
SCHEMBL30656008 0.86 MAPK14 (0.38) CNR2ADAM17KMT2A
SCHEMBL30656066 0.85 SCN9A (0.35) CNR2ADAM17CD274ADAMTS4MMP3
SCHEMBL24485706 0.83 SLC26A4 (0.49) CNR2ANO1KMT2ASLC26A4
SCHEMBL29629637 0.83 SLC26A4 (0.49) CNR2ANO1KMT2ASLC26A4
SCHEMBL30656334 0.83 CYP4F2 (0.40) ADAM17CD274ANO1ADAMTS4MMP3
SCHEMBL30656053 0.82 SMO (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed