Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 2/20 | 0.32 |
| ▸ | ADAMTS1 | Q9UHI8 | 2/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656112 | 0.97 | CD274 (0.35) | CD274ADAM17CNR2DGAT2HDAC6 | |
| SCHEMBL30656046 | 0.93 | CD274 (0.41) | CD274ADAM17CNR2DGAT2ADAMTS4 | |
| SCHEMBL30656121 | 0.90 | CNR2 (0.38) | CD274ADAM17CNR2CNR1ABL1 | |
| SCHEMBL30656091 | 0.85 | PARP15 (0.39) | CD274ADAM17 | |
| SCHEMBL30656008 | 0.85 | MAPK14 (0.38) | ADAM17CNR2 | |
| SCHEMBL24485688 | 0.84 | SLC26A4 (0.48) | L3MBTL1 | |
| SCHEMBL29629713 | 0.84 | SLC26A4 (0.48) | L3MBTL1 | |
| SCHEMBL30656066 | 0.84 | SCN9A (0.35) | CD274ADAM17CNR2ADAMTS4MMP3 | |
| SCHEMBL30656274 | 0.83 | ADAM17 (0.41) | CD274ADAM17CNR2CNR1DGAT2 | |
| SCHEMBL30656149 | 0.81 | PARP15 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532013-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-04-09 | — | — | EP | claimed |
| WO-2023227697-A1 | NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | claimed |