SCHEMBL30656334

SCHEMBL30656334

Cc1sc2ccc(OCc3cccnc3O)cc2c1C(=O)NC1(C(=O)O)CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
MMP3 P08254 2/20 0.38
MMP7 P09237 2/20 0.38
ADAM17 P78536 2/20 0.38
ADAMTS4 O75173 1/20 0.38
ADAMTS1 Q9UHI8 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.38
GPR132 Q9UNW8 3/20 0.37
MMP13 P45452 2/20 0.35
MMP2 P08253 1/20 0.35
MMP12 P39900 1/20 0.35
CXCR2 P25025 1/20 0.34
SLC26A4 O43511 2/20 0.34
ANO1 Q5XXA6 1/20 0.33
MMP1 P03956 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM4 Q14833 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656274 0.89 ADAM17 (0.41) MMP3MMP7ADAM17ADAMTS4ADAMTS1
SCHEMBL30656121 0.83 CNR2 (0.38) MMP3MMP7ADAM17ADAMTS4ADAMTS1
SCHEMBL30656215 0.80 MAPK14 (0.39) CYP4F2CYP4A11
SCHEMBL30656111 0.80 MMP1 (0.46) MMP3MMP7ADAM17ADAMTS4ADAMTS1
SCHEMBL30656046 0.79 CD274 (0.41) MMP3MMP7ADAM17ADAMTS4ADAMTS1
SCHEMBL30656015 0.78 ADAM17 (0.39) MMP3MMP7ADAM17ADAMTS4ADAMTS1
SCHEMBL31350322 0.78 EDNRA (0.38) SLC26A4MEN1KMT2A
SCHEMBL30656034 0.76 SLC26A4 (0.33) CXCR2SLC26A4MEN1KMT2AKDM4E
SCHEMBL30656189 0.76 SCN9A (0.36) GPR132SLC26A4
SCHEMBL30656207 0.76 CNR2 (0.38) CYP4F2CYP4A11MMP3MMP7ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed