SCHEMBL30656127

SCHEMBL30656127

Cc1ncsc1COc1ccc2sc(C)c(C(=O)NC3CCN(C)CC3)c2c1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 11/20 0.42
SSTR4 P31391 4/20 0.39
LMNA P02545 1/20 0.38
HSP90AA1 P07900 3/20 0.37
HSP90AB1 P08238 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656281 0.95 SLC6A5 (0.39) SLC6A5SSTR4
SCHEMBL30656039 0.85 HPGDS (0.40)
SCHEMBL30656225 0.85 CFD (0.34)
SCHEMBL26793496 0.84 SLC6A5 (0.49) SLC6A5SSTR4LMNA
SCHEMBL30656031 0.83 ESR1 (0.32)
SCHEMBL30656139 0.83 ESR1 (0.34)
SCHEMBL30656106 0.83 ESR1 (0.34)
SCHEMBL30656117 0.82 MEN1 (0.37)
SCHEMBL30656136 0.81 HPGDS (0.40)
SCHEMBL30714585 0.81 SLC6A5 (0.42) SLC6A5SSTR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed