SCHEMBL30656331

SCHEMBL30656331

CNC(=O)c1c(C)sc2ccc(OCc3cccnc3C(F)(F)F)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CD38 P28907 1/20 0.37
OPRL1 P41146 1/20 0.35
PPARD Q03181 4/20 0.35
PPARA Q07869 4/20 0.35
SLC26A4 O43511 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PPARG P37231 2/20 0.34
ICAM1 P05362 3/20 0.34
SELE P16581 3/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
EDNRA P25101 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656120 0.89 SLC26A4 (0.42) CD38OPRL1PPARDPPARASLC26A4
SCHEMBL31350334 0.89 CD38 (0.42) CD38OPRL1PPARDPPARASLC26A4
SCHEMBL30656197 0.88 SCN9A (0.35) CD38OPRL1PPARDPPARASLC26A4
SCHEMBL30655957 0.88 CD38 (0.38) CD38OPRL1PPARDPPARASLC26A4
SCHEMBL30656258 0.87 CD38 (0.37) CD38OPRL1L3MBTL1MAOAMAOB
SCHEMBL30656093 0.87 ALOX5 (0.39) ALDH1A1CD38L3MBTL1MAOBKMT2A
SCHEMBL30656226 0.87 CD38 (0.37) CD38OPRL1L3MBTL1MAOAMAOB
SCHEMBL30656066 0.86 SCN9A (0.35) CD38OPRL1PPARDPPARAPPARG
SCHEMBL30656176 0.85 CD38 (0.36) CD38OPRL1PPARDPPARAL3MBTL1
SCHEMBL30656016 0.85 CD38 (0.36) CD38OPRL1PPARDPPARAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed